Enantioselective reduction of ketoimines promoted by easily available (S)-proline derivatives

• Martina Bonsignore,
• Maurizio Benaglia,
• Laura Raimondi,
• Manuel Orlandi and
• Giuseppe Celentano

Beilstein J. Org. Chem. 2013, 9, 633–640, doi:10.3762/bjoc.9.71

• studies were also performed in order to elucidate the origin of the stereoselection. Keywords: chiral prolines; imine reduction; Lewis bases; organocatalysis; trichlorosilane; Introduction The reaction with stoichiometric amounts of trichlorosilane in the presence of a chiral catalyst is a well